Inovio Pharmaceuticals, disparada

8 respuestas
Inovio Pharmaceuticals, disparada
Inovio Pharmaceuticals, disparada
#1

Inovio Pharmaceuticals, disparada

 

Un laboratorio en el sur de California cree haber descubierto la vacuna contra el coronavirus

La vacuna podría estar disponible para el público a principios de este verano, lo que sería un marco de tiempo récord para el laboratorio del estado dorado, al cual se le acredita la creación de vacunas para el virus Zika, el Síndrome Respiratorio del Medio Oriente (MERS) y la vacuna contra el Ébola.

 https://www.univision.com/local/los-angeles-kmex/un-laboratorio-en-el-sur-de-california-descubre-la-vacuna-contra-el-coronavirus

Grafico, sube un 12%

https://finance.yahoo.com/quote/INO/chart/#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%3D 
#2

Re: Inovio Pharmaceuticals, disparada

+18%
#5

Re: Inovio Pharmaceuticals, disparada

+22%
#6

Re: Inovio Pharmaceuticals, disparada

Qué acción más loca, en marzo del 2.000 llegó a cotizar a 196$, y en noviembre de 2.008 a 60 céntimos de dólar !! Ahora mismo a las 19:50 lo hace a $3,96 ...

Buff

Aucune armée ne peut arrêter une idée dont le temps est venu - Victor Hugo

#8

Re: Inovio Pharmaceuticals, disparada

Análisis Inovio Pharmaceuticas (INO)



Perfil de la Empresa: Inovio Pharmaceuticals, Inc. (Inovio) es una compañía de biotecnología de la última etapa, que está implicado en el desarrollo de ácido desoxirribonucleico (ADN) inmunoterapias y vacunas se centraron en el tratamiento y la prevención de cánceres y enfermedades infecciosas. inmunoterapias basadas en el ADN de la compañía, en combinación con sus dispositivos de administración de la electroporación, genera respuestas inmunes, en las células T particulares, en el cuerpo para luchar contra las enfermedades diana. Se ha completado, actual o prevista de sus programas clínicos inmunoterapias Syncon para el virus del papiloma humano (VPH) precánceres y cánceres: provocada, la gripe, cáncer de próstata, pulmón / / cáncer de páncreas mama, virus de la hepatitis C (VHC), virus de la hepatitis B ( VHB), el virus de la inmunodeficiencia humana (VIH), el ébola, el Síndrome respiratorio Oriente Medio (MERS) y el virus Zika. Con su plataforma inmunoterapia, así como con su tecnología CELLECTRA entrega electroporación, tiene una cartera de productos de la etapa pre-clínicos y clínicos que han generado in vivo la respuesta inmune.


Comentarios: Inovio Pharmaceuticals rompió su canal bajista de largo plazo en diciembre de 2019. En estos momentos está rompiendo la pauta de continuidad y con un retroceso a corto plazo podrí estar interesante tomar posiciones alcistas. El punto importante a vigilar sería los 7 dólares. Si lo perdiera indicaría debilidad y podría finalizar la tendencia alcista. Tiene un posible objetivo sobre los 20 euros.

Los datos fundamentales indica un PER negativo por los resultados de explotación. Su deuda total es de 41% y su ratio de solvencia es 8,5. Mi ratio potencial sale 8 indicando crecimiento económico.

Conclusión: Oportunidad para atreverse a tomar posiciones en la Zona de Entrada. Siempre vigilando el punto importante.
 

Disclaimer de Contenido
Las inversiones en bolsa son de alto riesgo y se puede perder el capital que se vaya a invertir. El usuario debe tener el conocimiento suficiente del funcionamiento y del riesgo de los productos de inversión que vaya a utilizar. Las ideas o análisis no garantiza rentabilidades en las inversiones, ni tampoco garantiza la ausencia de pérdidas que el usuario realice.

#9

La vacuna del día le toca a Inovio


PLYMOUTH MEETING, Pa., May 20, 2020 /PRNewswire/ -- INOVIO (NASDAQ:INO) today announced the publication of the preclinical study data for IN0-4800, its COVID-19 DNA vaccine, demonstrating robust neutralizing antibody and T cell immune responses against coronavirus SARS-CoV-2. The study was published in the peer-reviewed journal Nature Communications titled, "Immunogenicity of a DNA vaccine candidate for COVID-19" by INOVIO scientists and collaborators from The Wistar Institute, the University of Texas, Public Health England, Fudan University, and Advaccine.


Dr. Kate Broderick, INOVIO's Senior Vice President of R&D and the Team Lead for COVID-19 vaccine development, said, "These positive preclinical results from our COVID-19 DNA vaccine (INO-4800) not only highlight the potency of our DNA medicines platform, but also build on our previously reported positive Phase 1/2a data from our vaccine against the coronavirus that causes MERS, which demonstrated near-100% seroconversion and neutralization from a similarly designed vaccine INO-4700. The potent neutralizing antibody and T cell immune responses generated in multiple animal models are supportive of our currently on-going INO-4800 clinical trials."


INO-4800 targets the major surface antigen Spike protein of SARS-CoV-2 virus, which causes COVID-19 disease. The studies demonstrated that vaccination with INO-4800 generated robust binding and neutralizing antibody as well as T cell responses in mice and guinea pigs. Importantly, the authors demonstrated virus neutralizing activity using three separate neutralization assays testing the vaccine's ability to generate antibodies which can block virus infection by: 1) an assay using live SARS-CoV-2 viruses; 2) an assay using a pseudo-virus assay, where another virus displays the SARS-CoV-2 Spike protein; and, 3) a novel high-throughput surrogate neutralization assay measuring the ability of INO-4800-induced antibodies to block SARS-CoV-2 Spike binding to the host ACE2 receptor. Study authors also detected these antibodies in the lungs of the vaccinated animals which could be important in providing protection from SARS-CoV-2. In addition, high levels of Spike-specific T cell responses were observed with INO-4800 vaccination, which could be important in mediating protection from the virus infection. Collectively, this preclinical dataset demonstrates that INO-4800 is a promising COVID-19 vaccine candidate against this emerging disease threat.


Dr. J. Joseph Kim, INOVIO's President & CEO, said, "INOVIO and our collaborators are working diligently to advance INO-4800 to help fight the current pandemic. We are planning to utilize these positive preclinical results along with our upcoming animal challenge data and safety and immune responses data from our Phase 1 studies to support rapidly advancing this summer to a large, randomized Phase 2/3 clinical trial."


INOVIO's swift progress in COVID-19 vaccine development is based on the ideal suitability of its DNA medicine platform to rapidly develop vaccines against emerging viruses with pandemic potential. INOVIO was the first to advance its DNA vaccine INO-4700 against MERS-CoV, a related coronavirus, into evaluation in humans in a collaboration with GeneOne Life Science and the Walter Reed Army Institute of Research. INO-4700 is the only MERS-CoV vaccine with positive data from a Phase 1/2a clinical trial, and INOVIO is currently preparing to initiate a larger Phase 2 vaccine trial for INO-4700 in the Middle East where most MERS viral outbreaks have occurred. These efforts are supported by CEPI funding.


About INO-4800


INO-4800 is INOVIO's DNA vaccine candidate created to protect against the novel coronavirus SARS-CoV-2, which causes COVID-19. INO-4800 was designed using INOVIO's proprietary DNA medicine platform rapidly after the publication of the genetic sequence of the coronavirus that causes COVID-19. INOVIO has deep experience working with coronaviruses and is the only company with a Phase 2a vaccine for a related coronavirus that causes Middle East Respiratory Syndrome (MERS).


About INOVIO's Global Coalition Advancing INO-4800


INOVIO has assembled a global coalition of collaborators, partners and funders to rapidly advance INO-4800. R&D collaborators to date include the Wistar Institute, the University of Pennsylvania, the University of Texas, Fudan University and the Laval University. INOVIO has partnered with Advaccine and the International Vaccine Institute to advance clinical trials of INO-4800 in China and South Korea, respectively. INOVIO is also assessing preclinical efficacy of INO-4800 in several animal challenge models with Public Health England (PHE) and Commonwealth Scientific and Industrial Research Organization (CSIRO) in Australia. INOVIO is also working with a team of contract manufacturers including VGXI, Inc., Richter-Helm BioLogics, and Ology Biosciences to produce INO-4800 and seeking additional external funding and partnerships to scale up the manufacturing capacities to satisfy the urgent global demand for a safe and effective vaccine. To date, the Coalition for Epidemic Preparedness Innovations (CEPI), the Bill & Melinda Gates Foundation, and the US Department of Defense have contributed significant funding to the advancement and manufacturing of INO-4800.


About INOVIO's DNA Medicines Platform


INOVIO has 15 DNA medicine clinical programs currently in development focused on HPV-associated diseases, cancer, and infectious diseases, including coronaviruses associated with MERS and COVID-19 diseases being developed under grants from the Coalition for Epidemic Preparedness Innovations (CEPI). DNA medicines are composed of optimized DNA plasmids, which are small circles of double-stranded DNA that are synthesized or reorganized by a computer sequencing technology and designed to produce a specific immune response in the body.


INOVIO's DNA medicines deliver optimized plasmids directly into cells intradermally or intramuscularly using INOVIO's proprietary hand-held smart device called CELLECTRA®. The CELLECTRA device uses a brief electrical pulse to reversibly open small pores in the cell to allow the plasmids to enter, overcoming a key limitation of other DNA and other nucleic acid approaches, such as mRNA. Once inside the cell, the DNA plasmids enable the cell to produce the targeted antigen. The antigen is processed naturally in the cell and triggers the desired T cell and antibody-mediated immune responses. Administration with the CELLECTRA device ensures that the DNA medicine is efficiently delivered directly into the body's cells, where it can go to work to drive an immune response. INOVIO's DNA medicines do not interfere with or change in any way an individual's own DNA. The advantages of INOVIO's DNA medicine platform are how fast DNA medicines can be designed and manufactured, the stability of the products which do not require freezing in storage and transport, and the robust immune response, safety profile, and tolerability that have been demonstrated in clinical trials.


With more than 2,000 patients receiving INOVIO investigational DNA medicines in more than 6,000 applications across a range of clinical trials, INOVIO has a strong track record of rapidly generating DNA medicine candidates with potential to meet urgent global health needs.

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