Re: Farmas USA
coñooo, no me acordaba Mugi, solo recordaba los que estabamos recientemente jugando el metesaca.
QUIERO UN PATADON PA'RRIBA YA MISMOOOOOO!!!!!
HZNP
Re: Farmas USA
ARNA
Del Osborne comentando el ER y la sesión de preguntas y respuestas sobre las similitudes y diferencias entre el ozanimod de CELGy el etrasimod de ARNA
it was determined that Ozanimod had uncharacterized metabolites which caused the FDA to not accept the NDA for the drug. With Etrasimod being closely compared to Ozanimod, Arena had to step forward and speak about whether or not similar concerns would exist in its candidate.
What management stated was that it was very familiar with both drugs, has run testing on both in a lab and that it sees no similar issues with Etrasimod. Essentially, Arena management stated that it would appear that Ozanimod is a step up from Celgene's Gilenya, but falls short of being the next generation in treatment. Arena indicated that the safety profile, dosing profile, and half-life characteristics of Etrasimod take treatment to the next level.
Arena's confidence was high, and while investors cannot ignore the risks, the potential here seems to be great. Ozanimod hit its hurdle as a treatment for MS, a treatment that Etrasimod is not yet chasing. This means that both drugs could see decent market penetration once ultimately approved. The 1-year setback experienced by Celgene should be something that will help Arena as it tries to attract investment dollars or potential partners.
Etrasimod
treatment of multiple immune and inflammatory diseases.
- Ulcerative colitis (UC): Positive Phase 2 data achieved in March 2018 and the company intends to initiate a Phase 3 program in late 2018.
- Crohn's disease (CD): The company is in the planning stage and working on a development path forward.
- Primary biliary cholangitis (PBC): A Phase 2 clinical trial is currently enrolling patients.
Ralinepag
selective prostacyclin receptor agonist intended for the treatment of pulmonary arterial hypertension (PAH). Arena intends to initiate two standalone, Phase 3 registrational studies, as well as additional differentiation studies, in the second half of 2018
Olorinab (formerly known as APD371)
intended for the potential treatment of visceral pain, specifically pain associated with Crohn's disease. This program has had a slower than desired
positive feedback as opioid addiction remains a central news topic discussion.
plans to complete enrollment in its Phase 2 trial in Q2 2018, and anticipates publishing results in Q3 2018.
Re: Farmas USA
Re: Farmas USA
Re: Farmas USA
Re: Farmas USA
HZNP
me quede como las vacas viendo pasar el tren,
diario por ahora