Re: Farmas USA
Que patrones tienen alta fiabilidad segun tus libros?
CÓDIGO AMIGO
Que patrones tienen alta fiabilidad segun tus libros?
Donde pones las alertas?
TGTX
Lo de hace unos meses fue Topline
http://ir.tgtherapeutics.com/releasedetail.cfm?ReleaseID=1028913
TG-1101 plus ibrutinib achieved 78% ORR, with 7% Complete Responses (CR), compared to 45% ORR with 0% CR's for Ibrutinib Alone, p < 0.001 (median follow-up 11.4 months), with all responses now confirmed as per iwCLL 2008 criteria
Combination of TG-1101 and ibrutinib resulted in 19% Minimal Residual Disease (MRD) negativity compared to 2% for Ibrutinib Alone, p < 0.01
A trend in improvement of PFS was observed with the combination of TG-1101 plus ibrutinib compared to ibrutinib alone (Hazard Ratio=0.559; p=NS)
The combination was well tolerated and TG-1101 did not appear to alter the safety profile of ibrutinib monotherapy, apart from infusion related reactions associated with TG-1101 which were primarily Grade 1/2