Chicharros USA - bolsa internacional (6292/11819)

#50330

Re: Chicharros USA - bolsa internacional

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15/05/20 00:00

Que broker utilizas pat?

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#50331

Re: Chicharros USA - bolsa internacional

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15/05/20 01:33

Tenía hace mucho tiempo Renta 4, pero era una ruina, así que me cambié a De Giro. Si ellos no estuvieran probablemente tendría que dejar todo este tema porque yo no voy a largo, voy aqui te pillo aquí te mato..

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#50332

Re: Chicharros USA - bolsa internacional

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15/05/20 10:22

DENN

https://investorplace.com/2020/05/dennys-earnings-boost-denn-stock-up/

Pues aquí sigo si. Mi posición en esta es de las mas fuertes que tengo y con un precio cerca de los 10,50$.

Suerte.

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#50333

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15/05/20 10:44

IMGN

Aparte de la participación prevista en ASCO para el 29 de mayo, la empresa comunica hoy la presentación de resultados preclínicos en relacion a la molécula IMGN151. La presentacion tendrá lugar en el Amercian Association for Cancer Research, entre el 22 y 24 de junio.

POSTER PRESENTATION

Title: “IMGN151: A Next Generation Folate Receptor Alpha Targeting Antibody Drug Conjugate Active Against Tumors with Low, Medium, and High Receptor Expression”
Day/Time: Monday, June 22, 2020 at 9:00 AM ET
Session Category: Experimental and Molecular Therapeutics
Session Title: Antibody Drug Conjugates
Abstract: 2890

IMGN151 activity was characterized against cell lines and xenograft models with a wide range of FRα expression and compared to mirvetuximab soravtansine (IMGN853). Cell lines and xenograft models originated from ovarian, endometrial, breast, and cervical cancer.
In tumor cells with medium and high FRα expression, IMGN151 boosted antibody binding events and payload delivery by 100% and 170%, respectively.
IMGN151 increased ADC half-life by 60 hours and conjugate exposure in vivo by 40%, as compared to IMGN853.
In vitro, IMGN151 was up to 200 times more active against four FRα-medium cell lines. IMGN151 also had better bystander killing activity in a mixed culture of target-positive and negative cells.
In vivo, IMGN151 induced complete tumor regressions of human tumor xenograft models with high, medium, and low FRα expression. All tested doses were well tolerated.