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Participaciones del usuario Dunki - Contenidos recomendados

30/01/18 10:01
Ha respondido al tema Aryzta AG.
Pues hoy continua bajando, habrá que estar atento para pescar algo cuando frene la caída. Le voy a dar un voto de confianza a Paramés.
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26/12/16 00:39
Ha respondido al tema Consejos para empezar el 2017
Pues mi opinión es que te fijaras en los gestores de los fondos y sus resultados a 3-5 años pero a dos años no es tan fácil tener buenos resultados si no arriesgas. A titulo de ejemplo: Renta 4 Pegasus para retorno absoluto - Miguel Jimenez Renta 4 Nexus para mixto flexible - algo más de riesgo - Miguel Jiménez azValor Internacional - renta variable europea - Alvaro Guzman Sin resultados pero de gestor fiable en teoría: Cobas en sus modalidades. Suerte con tu puntería
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21/12/16 14:16
Ha respondido al tema Farmas USA
LXRX http://seekingalpha.com/news/3231901-lexicon-pharmas-sotagliflozin-successful-second-late-stage-study-type-1-diabetics-shares-13?uprof=45#email_link
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11/09/16 18:49
Ha respondido al tema Farmas USA
NVAX http://seekingalpha.com/instablog/498952-bret-jensen/4915655-sunday-review-2-biotech-picks-and-week-1-fantasy-football-sleepers?source=email_rt_author_readmore&uprof=45&isDirectRoadblock=false
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17/08/16 14:48
Ha respondido al tema Farmas USA
VRX Por si a alguien le interesa http://seekingalpha.com/article/4000196-valiant-shorts-debunked-new-price-target-38_59?uprof=45&isDirectRoadblock=false
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07/08/16 20:22
Ha respondido al tema Farmas USA
http://seekingalpha.com/instablog/498952-bret-jensen/4906433-3-small-cap-biotech-trading-ideas-week-ahead?source=email_rt_author_readmore&app=1&uprof=45&isDirectRoadblock=false
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31/07/16 20:31
Ha respondido al tema Farmas USA
2 Small Attractive Vaccine Plays With Upcoming Catalysts Jul 31 2016, 11:40 Includes: DVAX, NVAX Novavax, Inc. (NASDAQ:NVAX) is a clinical-stage small vaccine maker which focuses on recombinant nanoparticle vaccines and adjuvants. The company produces its vaccines using its proprietary recombinant nanoparticle vaccine technology and has several near term market catalysts on the horizon. The company currently sports a market capitalization of approximately $2 billion and trades around $7.30 a share. Pipeline: Novavax' product pipeline includes an important respiratory syncytial virus (RSV) vaccine candidate in Phase III clinical trials for elderly and maternal immunization; a pediatric RSV candidate in Phase I clinical trial; seasonal quadrivalent influenza and pandemic H7N9 vaccines in Phase II clinical trials; vaccine candidate against Ebola Virus in Phase I clinical trial, a combination respiratory vaccine candidate and seasonal influenza vaccine candidate in pre-clinical trial; and a rabies G protein vaccine candidate in Phase I/II clinical trial. The company also has pre-clinical stage programs for various infectious diseases, including the Middle East respiratory syndrome coronavirus; and develops technology for the production of immune stimulating saponin-based adjuvants. The key near term catalyst for Novavax is going to be a key Phase 3 trial readout on a vaccine it is developing to combat RSV. These results should be out by the end of September. The company estimates there are some ~37 million RSV infections annually in the US, EU, and Asia resulting in an estimated annual cost burden of roughly $80 to $100 billion. In the elderly (>65) U.S. population alone, there are ~ 4.3 million RSV, Influenza, and Pneumonia infections which result in over 800,000 hospitalizations and 50,000 deaths annually. RSV F Vaccine (Respiratory Syncytial Virus Fusion Protein Vaccine) What it Does: It is a novel vaccine developed using recombinant nanoparticle technology to target the fusion protein, or F-protein, of the RSV virus. Key Differentiator(s): · RSV is a very common illness having potentially very serious impacts (including death) on the very young and the very old. · EFFICACY: It is the First and ONLY candidate to demonstrate protection from RSV in any population, breakthrough efficacy in older adults, breakthrough proof-of-principle in maternal immunization. Phase / Status: · Key Phase III readout is expected as mentioned above is due out by end of the third quarter after having been fast tracked for older adults. Assuming positive data, the company will file a BLA early in 2017. · Top-line Phase II clinical trial results were positive, indicating the candidate is safe, well-tolerated and effective at protecting infants when they are most at risk, via maternal immunization. A Phase III trial is now underway in the United States, South America, Africa and Australia, and is now being expanded into Mexico, Europe and Asia in alignment with intentions of an $89M grant from the Bill & Melinda Gates Foundation. Preliminary results are now expected in 2018. · A phase 1 clinical trial underway for pediatric use (6 mos-5 years). · A phase 2 clinical trial being planned to assess the addition of a booster for older adults. Expected Market: The company estimates worldwide RSV F Vaccine revenue opportunity at $6-8 billion per year. Initially, Novavax is some 100 million individuals for RSV immunization in the U.S. Market including pregnancies > 27 weeks, infants & toddlers, high risk patients between 50-59 years old, and all adults over 60. The price range of existing comparable vaccines is $30-$75. Other Considerations: · This important vaccine was awarded a grant from the Bill and Melinda Gates Foundation for up to $89 million of development support with the goal of protecting infants via affordable maternal immunization in the developing world. · Has the potential to be useful for other emerging viruses such as Ebola and H7N9. Balance Sheet & Analyst Support: The financial results for the quarter ended March 31, 2016 showed a cash burn rate of approximately $70 million, including significant R&D expenses related to ongoing trials. Novavax has over $425 million of cash on hand after recently strengthening its balance sheet through a $325 million convertible note offering. Additionally, Novavax, is adding staff in preparation for a commercial launch of the RSV F Vaccine in the United States, assuming positive study results soon and filing of a BLA (Biologic License Application) in 2017. Novavax is simultaneously exploring a number of potential partnerships for commercialization of the RSV F vaccine outside of the United States, in anticipation of the upcoming Phase III data results announcements. Looking ahead to the expected Phase III RSV vaccine data from Novavax by the end of September, Piper Jaffray indicated that Novavax could be an acquisition target by a larger vaccine player in late June, and recommends the stock as Buy with a $14 price target. Piper's analyst further noted "Based on the Phase II study, we are confident the RSV Phase III trial is sufficiently powered to achieve statistical significance..." The month before, FBR Capital also recommended Novavax as a Buy with a price target of $17, indicating the global expansion of the Phase III trial for maternal immunizations is aligned with the intentions of the grant it was awarded, and in the near term they remain "focused on the anticipated 3Q16 release of top-line data from the RESOLVE Phase III study in elderly adults as a potentially positive catalyst for the stock." The company is highly likely to receive approval for its RSV vaccine and have it on the market in 2017. Novavax is well funded, has a diverse pipeline aimed at addressable markets and at some point could also make a logical acquisition target. In addition, the stock has been hurt by the bear market that has existed on the biotech sector over the past year which seems now to be ended. The shares 52 week high is just over $14.00 a share, just under the median price target on the stock by the analysts that cover it. RSV puts over 200,000 elderly individuals in the hospital every year just in the States. The vaccine should be a major source of revenues in coming years and if Novavax's pipeline continues to develop, it will be the first of several significant recurring income streams.
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01/06/16 21:58
Ha respondido al tema Farmas USA
Imagino que todo depende de la gestión económica, no es lo mismo entrar con 12k que con 100k
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29/05/16 20:41
Ha respondido al tema Farmas USA
Felicidades Framus, muchas gracias por tus aportaciones. Ojalá que algún día no lejano te podamos corresponder con alguna aportación de otra bio, aunque difícil que sea con el grado de conocimiento que tienes de nvax.
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